The University of Western Australia

UWA Staff Profile

Ipsum Lorem

Dr Donna Geddes

Senior Research Fellow
Chemistry and Biochemistry, School of

Contact details
Address
School of Chemistry and Biochemistry
The University of Western Australia (M310)
35 Stirling Highway
CRAWLEY WA 6009
Australia
Phone
+61 8 6488 7006
Fax
+61 8 6488 7086
Email
donna.geddes@uwa.edu.au
Location
Room 2.04, Bayliss Building, Perth campus
Qualifications
DMU PostGradDipSc PhD W.Aust.
Biography
Donna is the director of the Human Lactation Research Group. Donna originates from a medical imaging background with an emphasis in ultrasound imaging. She has integrated this modality into many of the group’s studies providing a ‘window’ to different physiological processes during lactation. Her findings have attracted much international attention and she is often requested to speak at both International and National Scientific Meetings. She is a member of the Nutrition Society of Australia and Secretary for the International Society for Research in Human Milk and Lactation.
Key research
Donna has a broad range of research interests in the physiology of lactation extending from basic to applied research. In particular she utilizes her ultrasound imaging skills to assess the lactating breast (anatomy, milk ejection and blood flow) as well as the infant (suck-swallow-breathe, gastric emptying and body composition). Her current interests include understanding the role of breastmilk in appetite control and the development of breastfeeding in the preterm infant.
Publications
Sakalidis VS, Geddes DT. Suck-Swallow-Breathe Dynamics in Breastfed Infants. J
Hum Lact. 2016 May;32(2):201-11. doi: 10.1177/0890334415601093. Epub 2015 Aug 28.
Review. PubMed PMID: 26319112. PDF OR11

Perrella SL, Geddes DT. A Case Report of a Breastfed Infant's Excessive Weight
Gains over 14 Months. J Hum Lact. 2016 May;32(2):364-8. doi:
10.1177/0890334415610769. Epub 2015 Oct 15. PubMed PMID: 26470877. PDF OCA 1

McLeod G, Sherriff J, Hartmann PE, Nathan E, Geddes D, Simmer K. Comparing
different methods of human breast milk fortification using measured v. assumed
macronutrient composition to target reference growth: a randomised controlled
trial. Br J Nutr. 2016 Feb 14;115(3):431-9. doi: 10.1017/S0007114515004614. Epub
2015 Dec 2. PubMed PMID: 26627899. PDF P211

Alsaweed M, Lai CT, Hartmann PE, Geddes DT, Kakulas F. Human milk miRNAs
primarily originate from the mammary gland resulting in unique miRNA profiles of
fractionated milk. Sci Rep. 2016 Feb 8;6:20680. doi: 10.1038/srep20680. PubMed
PMID: 26854194; PubMed Central PMCID: PMC4745068. PDF P204

Trend S, Strunk T, Lloyd ML, Kok CH, Metcalfe J, Geddes DT, Lai CT, Richmond
P, Doherty DA, Simmer K, Currie A. Levels of innate immune factors in preterm and
term mothers' breast milk during the 1st month postpartum. Br J Nutr. 2016 Apr
14;115(7):1178-93. doi: 10.1017/S0007114516000234. Epub 2016 Feb 19. PubMed PMID:
26891901.

Geddes DT, Sakalidis VS. Ultrasound Imaging of Breastfeeding-A Window to the
Inside: Methodology, Normal Appearances, and Application. J Hum Lact. 2016
May;32(2):340-9. doi: 10.1177/0890334415626152. Epub 2016 Feb 29. PubMed PMID:
26928319.

Kakulas F, Geddes DT, Hartmann PE. Breastmilk Is Unlikely to Be a Source of
Mesenchymal Stem Cells. Breastfeed Med. 2016 Apr;11:150-1. doi:
10.1089/bfm.2016.0021. Epub 2016 Mar 9. PubMed PMID: 26959399.

Cannon AM, Sakalidis VS, Lai CT, Perrella SL, Geddes DT. Vacuum
characteristics of the sucking cycle and relationships with milk removal from the
breast in term infants. Early Hum Dev. 2016 May;96:1-6. doi:
10.1016/j.earlhumdev.2016.02.003. Epub 2016 Mar 8. PubMed PMID: 26964010.

Tie WJ, Gardner H, Lai CT, Hepworth AR, Al-Tamimi Y, Paech MJ, Hartmann PE,
Geddes DT. Changes in milk composition associated with pethidine-PCEA usage after
Caesarean section. Matern Child Nutr. 2016 Apr 4. doi: 10.1111/mcn.12275. [Epub
ahead of print] PubMed PMID: 27040350.

Alsaweed M, Lai CT, Hartmann PE, Geddes DT, Kakulas F. Human Milk Cells and
Lipids Conserve Numerous Known and Novel miRNAs, Some of Which Are Differentially
Expressed during Lactation. PLoS One. 2016 Apr 13;11(4):e0152610. doi:
10.1371/journal.pone.0152610. eCollection 2016. PubMed PMID: 27074017; PubMed
Central PMCID: PMC4830559.

Sakalidis VS, Geddes DT. Independent Study Module for Lactation Consultants:
"Suck-Swallow-Breathe Dynamics in Breastfed Infants". J Hum Lact. 2016
May;32(2):393-5. doi: 10.1177/0890334416639575. PubMed PMID: 27084971.

Alsaweed M, Lai CT, Hartmann PE, Geddes DT, Kakulas F. Human Milk Cells
Contain Numerous miRNAs that May Change with Milk Removal and Regulate Multiple
Physiological Processes. Int J Mol Sci. 2016 Jun 17;17(6). pii: E956. doi:
10.3390/ijms17060956. PubMed PMID: 27322254; PubMed Central PMCID: PMC4926489.

Melnik BC, Kakulas F, Geddes DT, Hartmann PE, John SM, Carrera-Bastos P,
Cordain L, Schmitz G. Milk miRNAs: simple nutrients or systemic functional
regulators? Nutr Metab (Lond). 2016 Jun 21;13:42. doi: 10.1186/s12986-016-0101-2.
eCollection 2016. PubMed PMID: 27330539; PubMed Central PMCID: PMC4915038.

Hassiotou F, Geddes DT.
Immune cell-mediated protection of the mammary gland and the infant during breastfeeding.
Advances in Nutrition 6(3): 267-275 (2015)

K Simmer, C Kok, K Nancarrow, A R Hepworth and D T Geddes.
Novel feeding system to promote establishment of breastfeeds after preterm birth: a randomized controlled trial
Journal of Perinatology doi: 10.1038/jp.2015.184: 1-6 (10 December 2015)

Alsaweed M., Hartmann P.E., Geddes D.T., Kakulas F.
MicroRNAs in breastmilk and the lactating breast: Potential immunoprotectors and developmental regulators for the infant and the mother.
International Journal of Environmental Research and Public Health 12: 13981-14020 (2015)

Anna M. Cannon, Foteini Kakulas, Anna R. Hepworth, Ching Tat Lai, Peter E. Hartmann and Donna T. Geddes.
The Effects of Leptin on Breastfeeding Behaviour
Int. J. Environ. Res. Public Health 12(10): 12340-12355 (2015)

McClellan, H. L.; Kent, J. C.; Hepworth, A. R.; Hartmann, P. E.; Geddes, D. T.
Persistent nipple pain in breastfeeding mothers associated with abnormal infant tongue movement.
Int. J. Environ. Res. Public Health 12(9): 10833-10845 (2015)

Twigger A-J, Lai CT, Chetwynd E, Stuebe AM, Blancafort P, Hartmann PE, Geddes DT, Kakulas F. Gene expression in breastmilk cells is associated with maternal and infant characteristics. Scientific Reports, Nature (accepted 2015)

Perrella SL, Lai CT, Geddes DT. Case report of nipple shield trauma associated with breastfeeding an infant with high intra-oral vacuum. BMC Pregnancy and Childbirth (accepted) (2015)

Gardner H, Kent JC, Lai CT, Mitoulas LR, Cregan MD, Hartmann PE, Geddes DT. Milk ejection patterns: an intra- individual comparison of breastfeeding . BMC Pregnancy and Childbirth (accepted) (2015)

Perrella, S. L.; Hepworth, A. R.; Simmer, K. N.; Geddes, D. T. Influences of breast milk composition on gastric emptying in preterm infants. Journal of Pediatric Gastroenterology and Nutrition 2015, 60, 264-271 (2015)

Alsaweed M, Hepworth AR, Lefevre C, Hartmann PE, Geddes DT, Hassiotou F. Human milk microRNA and total RNA differ depending on milk fractionation. Journal of Cellular Biochemistry DOI: 10.1002/jcb.25207 (2015)

McLeod G, Simmer K, Sherriff J, Nathan E, Geddes D, Hartmann P. Feasibility study: Assessing the influence of macronutrient intakes on preterm body composition, using air displacement plethysmography. Journal of Paediatrics and Child Health. doi:10.1111/jpc.12893 (2015)

Gardner, H; Kent, .JC., Hartmann, P.E. and Geddes, D.T. Asynchronous milk ejection in human lactating breast: Case Series. Journal of Human Lactation (2015)

Perrella, S.L.; Hepworth, A.R.; Gridneva, Z.; Simmer, K.N.; Hartmann, P.E. and Geddes, D.T. Gastric emptying and curding of pasteurized donor human milk and mother's own milk in preterm infants. Journal of Pediatric Gastroenterology and Nutrition 60(2): 264-271 (2015)

McLeod G, Simmer K, Sherriff J, Nathan E, Geddes D, Hartmann P. Feasibility study: Assessing the influence of macronutrient intakes on preterm body composition, using air displacement plethysmography. Journal of Paediatrics and Child Health. doi:10.1111/jpc.12893 (2015)

Mortazavi SN, Geddes D, Hassanipour F. Modeling of milk flow in mammary ducts in lactating human female breast. Conference proceedings : Annual International Conference of the IEEE Engineering in Medicine and Biology Society IEEE Engineering in Medicine and Biology Society Annual Conference 5675-5678 (2014)

Mortazavi SN, Geddes D, Hassiotou F, Hassanipour F. Mathematical analysis of mammary ducts in lactating human breast. Conference proceedings : Annual International Conference of the IEEE Engineering in Medicine and Biology Society IEEE Engineering in Medicine and Biology Society Annual Conference 5687-5690 (2014)

Hassiotou, F. and Geddes, D.T. Programming of appetite control during breastfeeding as a preventative strategy against the obesity epidemic. Journal of Human Lactation 30(2): 136–142 (2014)

Bode, L.; McGuire, M.; McGuire, M.K.; Rodriguez, J.M.; Geddes, D.T.; Hassiotou F. and Hartmann P.E. It’s alive: Microbes and cells in human milk and their potential benefits to mother and infant. Advances in Nutrition 5: 1–3 (2014)

Mortavazi, N.; Hassiotou, F.; Geddes, D.T. and Hassanipour, F. Mathematical modeling of mammary ducts in lactating human females. Journal of Biomechanical Engineering Nov 1. doi: 10.1115/1.4028967. [Epub ahead of print] (2014)

Perrella, S.L.; Hepworth, A.R.; Simmer, K.N.; Hartmann, P.E. and Geddes, D.T. Repeatability of gastric volume measurements and intragastric content using ultrasound in preterm infants. Journal of Pediatric Gastroenterology and Nutrition 59(2):254-263 (2014)

Sakalidis, V. S., Kent, J. C., Garbin, C. P., Hepworth, A. R., Hartmann, P. E., Geddes, D. T., Longitudinal changes in suck-swallow-breathe, oxygen saturation, and heart rate patterns in term breastfeeding infants. Journal Human Lactation 2013, 29:2

Perrella, S. L., Hepworth, A. R., Simmer, K. N., Geddes, D. T., Validation of ultrasound methods to monitor gastric volume changes in preterm infants. J Pediatr Gastroenterol Nutrition 2013, 57:6

McLeod, G., Geddes, D., Nathan, E., Sherriff, J., Simmer, K., Hartmann, P., Feasibility of using ultrasound to measure preterm body composition and to assess macronutrient influences on tissue accretion rates. Early Hum Dev 2013 89:8

Hassiotou, F., Hepworth, A. R., Williams, T. M., Twigger, A. -J., Perrella, S., Lai, C. T., Filgueira, L., Geddes, D. T., Hartmann, P. E., Breastmilk cell and fat contents respond similarly to removal of breastmilk by the infant. PLoS ONE 2013 8:11

Hassiotou, F., Geddes, D. T., Hartmann, P. E.
Cells in human milk: state of the science. J Hum Lact 2013 29:2

Hassiotou, F., Geddes, D., Anatomy of the human mammary gland: Current status of knowledge. Clin Anat, 2012 Vol 26:1

Gridneva, Z., Hepworth, A. R., Skwierczynska, A. M., Hartmann, P. E., Geddes, D. T.
Effect of volume and macronutrients on gastric emptying in term breastfed infants – an ultrasonic assessment. Nutrition Society of Australia, 2013

Lau C, Geddes DT, Mizuno K, Schaal B. The Development of Oral Feeding Skills in Infants. International Journal of Pediatrics.

Geddes DT, Prescott SL. Developmental Origins of Health and Disease: the role of breastmilk in preventing disease in the 21st century. Journal of Human Lactation 2013; 29(2):123-7

Garbin CP, Sakalidis VS, Chadwick LM, Whan E, Hartmann PE. Geddes DT. Evidence of Improved Milk Intake after Frenotomy – a case study. Pediatrics, 2013;DOI: 10.1542/peds.2012-2651

Sakalidis VS, Kent JC, Garbin, CP, Hepworth A,R Hartmann PE, Geddes DT. Longitudinal changes in suck-swallow-breathe, oxygen saturation, and heart rate patterns in term breastfeeding infants. Journal of Human Lactation 2013; 29(2):236-45

Sakalidis VS, Williams TM, Hartmann PE, Geddes DT. Ultrasound Imaging of Infant Sucking Dynamics during the Establishment of Lactation. Journal of Human Lactation 2013 May;29(2):205-13

Sakalidis VS, McClellan H, Hepworth A, Kent J, Lai CT, Hartmann PE, Geddes DT. Oxygen saturation and suck-swallow-breathe coordination of term infants during breastfeeding and feeding from a teat releasing milk only with vacuum. International Journal of Pediatrics. 2012:130769

Sakalidis VS, Williams TM, Hartmann PE, Geddes DT. A comparison of early sucking dynamics during breastfeeding after caesarean section and vaginal birth. Breastfeeding Medicine 2013 Feb;8(1):79-85.

Perrella S, Nathan E, Hartmann PE, Geddes DT. Influences on breastfeeding outcomes for healthy term and preterm/sick infants. Breastfeeding Medicine. 2012;7:255-61.

McClellan HL, Hepworth AR, Garbin CP, Rowan MK, Deacon J, Hartmann PE, Geddes DT. Nipple pain during breastfeeding with or without visible trauma. Journal of Human Lactation. 2012;28:511-21.

Hassiotou F, Geddes DT, Hartmann PE. Cells in Human Milk: state of the science. Journal of Human Lactation. 2013; 29(2):171-82

Hassiotou F, Geddes DT. Antomy of the human mammary gland: Current status of knowledge. Journal of Clinical Anatomy, 2012
Roles, responsibilities and expertise
Editorial Positions
•Guest Editor – ‘Down Under’ edition – Journal of Human Lactation
•Guest Co-editor – International Journal of Pediatrics (Special Edition Infant feeding, 2012)
•Consultant Editor – Journal of Human Lactation
Reviewer Scientific Journals
•Early Human Development
•European Journal of Surgery
•Journal of Human Lactation
•Breastfeeding Medicine
•Mary Paton Award Judge
•Australian Breastfeeding Association
•Pediatric Research
•Acta Pediatrica
•Pediatrics
•Breastfeeding Review
Future research
Donna’s future research encompasses the appetite control mechanisms of the breastfed infant.
Funding received
•2007-2016: Medela AG – Research Fellow/Chief Investigator
•Woman and Infants Research Foundation (WIRF) Grant for researching the relationship between sucking, swallowing and breathing in healthy term breastfeeding infants and those experiencing difficulties.
Memberships
•Nutrition Society of Australia
•International Society for Research in Human Milk and Lactation
•Australian Sonographers Accreditation Board
Honours and awards
•2008 Early Career Research Award for ISRHML
•2008 Certificate of Distinction for Innovative Research from the Raine Foundation
•2007 Healthy Children Faculty Award
Previous positions
•Postdoctoral Research Associate, University of Western Australia
•Senior Ultrasonographer , Perth Imaging
Patents
•Carr, L., Dettling, M., Luzbetak, M.A.,
Silver, B.H., Sutrina, T., Hartmann, P.E., Mitoulas, L., Geddes, D.T., Kent, J.C. Synchronized diaphragm breast pump pumping cycle pressure control system. World Intellectual Property Organisation – WO 2008/127991 A1. 23 October 2008
•Geddes, D.T. Method for yielding maximum expression in breastpumping. World Intellectual Property Organisation – WO 2008/034192 A1. 27 March 2008
•Hartmann, P.E. Geddes, D.T., Kent, J.C., Cregan, M.D. Breastpump. World Intellectual Property Organisation – WO 2007/059642 A1. 31 May 2007.
Useful links
http://humanlactationresearchgroup.com/

http://www.chembiochem.uwa.edu.au/research/human-lactation

http://www.chembiochem.uwa.edu.au/research#publications-10
Current projects
Appetite control factors in breastmilk
Gastric emptying of term and preterm infants
Milk removal during breast expression.
Research profile
Research profile and publications
 

The University of Western Australia

This Page

Last updated:
Tuesday, 3 November, 2015 2:39 PM

http://www.web.uwa.edu.au/117768