The University of Western Australia

UWA Staff Profile

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Peter McFawn

Dr Peter McFawn

Associate Lecturer
Human Sciences, School of

Contact details
Address
School of Human Sciences
The University of Western Australia (M311)
35 Stirling Highway
CRAWLEY WA 6009
Australia
Phone
+61 8 6488 3341
Fax
+61 8 6488 1025
Email
Peter.McFawn@uwa.edu.au
Qualifications
BSc PhD W.Aust.
Biography
A/Prof Peter McFawn is a graduate of UWA, with both his BSc and PhD. He then spent four years in a research fellowship position at Queens University in Canada before returning to UWA to take up his current position as an Associate Researcher, where he works closely with his former PhD supervisor, Prof. Howard Mitchell.
Key research
A/Prof McFawn primary research area is the respiratory physiology of airways from the mouth to the lungs, especially concerning the muscles associated with breathing. In healthy people the smooth muscle in the airways can be relaxed simply by taking a deep breath. However, people with medical problems such as asthma can suffer from hyper-tension of these muscles, making it difficult to breathe. As well as helping us to understand better how our bodies work, A/Prof McFawn's research can be directly applied to the health science and may one day help people with respiratory problems and diseases.
Collaborators
Peter Noble, Institute for Child Health Research (ICHR)
Alan James, Charles Gardener Hospital
Lyn Fernaders, Pharmacology, UWA
Publications
Noble, P.B., Sharma, A., McFawn, P.K., Mitchell, H.W. Airway narrowing in porcine bronchi with and without lung parenchyma, European Respiratory Journal, 26: pp 804-811 (2004)
Noble, P.B., Sharma, A., McFawn, P.K., Mitchell, H.W. Elastic properties of the bronchial mucosa: epithelial unfolding and stretch in response to airway inflation, Journal of Applied Physiology 97: pp 913-919 (2004)
Khangure, S.R., Noble, R.B., Sharma, A., Chia, P.Y., McFawn, P.K., Mitchell, H.W. Cyclical elongation regulates contractile responses of isolated airways, Journal of Applied Physiology, 97: pp 913-919 (2004)
Noble, P.B., McFawn, P.K., Mitchell, H.W. Intraluminal pressure oscillation enhances subsequent airway contraction in isolated bronchial segments, Journal of Applied Physiology, 96: pp 1161-1165 (2004)
Walker, J.K., Gainetdinov, R.R., Feldman, D.S., McFawn, P.K., Caron, M.G., Lefkowitz, R.J., Premont, R.T., Fisher, J.T. G Protein-coupled receptor kinase 5 regulates airway responses induced by muscarinic receptor activation, American Journal of Physiology: Lung Cell and Molecular Physiology, 286: pp L312-L319 (2004)
McFawn, P.K., Shen,L., Vincent, S.G., Mak, A., Van Eyk, J.E., Fisher, J.T. Calcium-independent contraction and sensitisation of airway smooth muscle by p21 activated protein kinase, American Journal of Physiology: Lung Cell and Molecular Physiology, 248: pp L863-L870 (2003)
McFawn, P.K., Forkert, L., Fisher, J.T. A new method to perform quantitative measurement of bronchoscopic images, European Respiratory Journal, 18; pp 817- 826 (2001)
Mitchell, H.W., Turner, J.D., Grey, P.R., McFawn, P.K. Compliance and stability of the broncial wall in a model of allergen-induced lung inflammation, Journal of Applied physiology, 86: pp 932-937 (1999)
McFawn, P.K., Gray, P.R., Thomas, J., Mitchell, H.W. Pulmonary inflammation without bronchial hyperresponsiveness in vivo or in vitro after sephadex instillation in pigs, Clinical and Experimental Pharmacology and Physiology, 26: pp 105-108 (1999)
Mitchell, H.W., Cvetkovski, R., Sparrow, M.P., Gray, P.R., McFawn, P.K. Concurrent measurement of smooth muscle shortening, lumen narrowing and flow to ACh in large and small bronchi, European Respiratory Journal, 12: pp 1053-1061 (1998)
McFawn, P.K., Mitchell, H.W. Effect of transmural pressure on preloads and collapse of immature bronchi, European Respiratory Journal, 10: pp 322-329 (1997)
McFawn, P.K., Mitchell, H.W. Bronchial compliance and wall structure during development of immature human and pig lung, European Respiratory Journal, 10: pp 27-34 (1997)
McFawn, P.K., Sparrow, M.P., Mitchell, H.W. Measurement of flow through perfused bronchial segments: Optimization of flow head resistance, European Respiratory Journal, 8: pp 161-166 (1995)
McFawn, P.K., Mitchell, H.W. Bronchial compliance in pre- and post- natal development, In: Second SIDS International Conference, eds. Walker, A.M., McMillen, C. Perinatology Press: pp 243-249.
Sparrow, M.P., McFawn, P.K., Omari, T.I., Mitchell, H.W. Activation of smooth muscle in the airway wall, force production and airway narrowing, The Canadian Journal of Physiology and Pharmacology, 70: pp 607-614 (1992)
Mitchell, H.W., McFawn, P.K., Sparrow, M.P. Increased narrowing of bronchial segments from immature pigs, European Respiratory Journal, 5: pp 207-212 (1992)
Mitchell, H.W., McFawn, P.K., Marriott, J.C., Sparrow, M.P. The relationship between smooth muscle shortening and resistance in isolated airways, In: Airway Wall Remodeling in the Pathogenesis of Asthma, Ed. Stewart, A.G. CRC Press, pp 227-244 (1997)
Funding received
HMRC Research Grants
Teaching
A/Prof Peter McFawn teaches at both the Singapore and Perth campuses. The courses he teaches in Perth are:

Unit Co-ordinator:
PHYL3340 Advanced Cellular Physiology
PHYL3350 Physiological Control Mechanisms

Lecturer:
PHYL2255 Physiology of Human Body Systems
PHYL2260 Physiology of Adaption and Stress
IDNT1121 Foundations of Human and Animal Biology
Graduate Entry Medical Programme (GEMP)

Lab Classes:
PHYL2245 Physiology of Cells
Current projects
•Using computer controlled oscillated muscles to study and measure stimulated breathing.
•Using cellular cultures of smooth muscle to determine the cellular components of responses to stress
•Studying the damage to airways and muscles from patients with chronic obstructive pulmonary disease (COPD)

Potential Student Projects
Looking at human COPD versus controls (PhD)
Research profile
Research profile and publications
 

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Last updated:
Tuesday, 3 November, 2015 2:39 PM