The University of Western Australia

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Dr Haibo Jiang

Lecturer (CMCA@Physics)
Microscopy, Characterisation and Analysis, Centre for (CMCA)

Contact details
Address
Centre for Microscopy, Characterisation and Analysis (CMCA)
The University of Western Australia (M010)
35 Stirling Highway
CRAWLEY WA 6009
Australia
Phone
+61 8 6488 8086
Email
haibo.jiang@uwa.edu.au
Location
Room 1.83, Physics Building, Perth campus
Biography
Dr. Haibo Jiang completed his PhD in Materials at University of Oxford, and continued for a postdoc in Prof. Chris Grovenor’s group working on nanoscale secondary ion mass spectrometry (NanoSIMS) for biomedical imaging, during which he demonstrated high-resolution direct visualization of lipids and peptides in cells and tissues. He moved to The University of Western Australia in 2015 as a Lecturer. Haibo’s research interests are focused on the development of novel analytical methods for biological applications, particularly multiplexed and high-resolution imaging of molecules with mass spectrometry imaging. His current projects involve further understanding of lipid transport, cellular cholesterol efflux and antimicrobial resistance.
Key research
Imaging Mass Spectrometry, lipid metabolism, NanoSIMS, antimicrobial resistance
Publications
1.He C, Hu X, Jung RS, Weston TA, Sandoval NP, Tontonoz P, Kilburn M, Fong LG, Young SG, Jiang H*. (2017) High-resolution imaging and quantification of plasma membrane cholesterol by NanoSIMS. Proceedings of the National Academy of Sciences, 2017, p.201621432.
2.Jiang H*, Passarelli M, Munro PM, Kilburn MR, West A, Dollery C, Gilmore I, Rakowska PD. High-resolution sub-cellular imaging by correlative NanoSIMS and electron microscopy of amiodarone internalisation by lung macrophages as the evidence for drug-induced phospholipidosis. Chemical Communications. 2017, 53, 1506 - 1509.
3.Hayouka, Z., Bella, A., Stern, T., Ray, S., Jiang, H., Grovenor, C.R. and Ryadnov, M.G., Binary Encoding of Random Peptide Sequences for Selective and Differential Antimicrobial Mechanisms. Angewandte Chemie International Edition. 2017, 56(28), pp.8099-8103.
4.Drozdz, M.M., Jiang, H., Pytowski, L., Grovenor, C. and Vaux, D.J., Formation of a nucleoplasmic reticulum requires de novo assembly of nascent phospholipids and shows preferential incorporation of nascent lamins. 2017, Scientific Reports, 7.
5.Pyne A, Pfeil MP, Bennett I, Ravi J, Iavicoli P, Lamarre B, Roethke A, Ray S, Jiang H, Bella A, Reisinger B, Daniel Yin, Benjamin Little, Juan C Muñoz-García, Eleonora Cerasoli, Peter J Judge, Nilofar Faruqui, Luigi Calzolai, Andre Henrion, Glenn J Martyna, Chris RM Grovenor, Jason Crain, Bart W Hoogenboom, Anthony Watts, Maxim G Ryadnov. Engineering monolayer poration for rapid exfoliation of microbial membranes. Chemical Science. 2017,8, 1105-1115
6.Kumar N, Drozdz M, Jiang H, Santos D, Vaux D. Nanoscale mapping of newly-synthesised phospholipid molecules in a biological cell using tip-enhanced Raman spectroscopy. Chemical Communications, 53(16), pp.2451-2454.
7.Jiang H, Kilburn MR, Decelle J, Musat N. NanoSIMS chemical imaging combined with correlative microscopy for biological sample analysis. Current Opinion in Biotechnology. 2016 Oct 31;41:130-5.
8.He C, Fong LG, Young SG, Jiang H*. NanoSIMS imaging: an approach for visualizing and quantifying lipids in cells and tissues. Journal of Investigative Medicine. 2016 Oct 28:jim-2016. (Invited)
9.Fong LG, Young SG, Beigneux AP, Bensadoun A, Oberer M, Jiang H, Ploug M. GPIHBP1 and Plasma Triglyceride Metabolism. Trends in Endocrinology & Metabolism. 2016, 27(7), pp.455-469.
10.Hickman-Lewis K, Garwood RJ, Brasier MD, Goral T, Jiang H, McLoughlin N, Wacey D. Carbonaceous microstructures from sedimentary laminated chert within the 3.46 Ga Apex Basalt, Chinaman Creek locality, Pilbara, Western Australia. Precambrian Research. 2016 Jun 30;278:161-78.
11.Neo DC, Zhang N, Tazawa Y, Jiang H, Hughes GM, Grovenor CR, Assender HE, Watt AA. Poly (3-hexylthiophene-2, 5-diyl) as a Hole Transport Layer for Colloidal Quantum Dot Solar Cells. ACS applied materials & interfaces. 2016 May 9;8(19):12101-8.
12.Bai M, Jiang H, Chen Y, Chen Y, Grovenor C, Zhao X, Xiao P. Migration of sulphur in thermal barrier coatings during heat treatment. Materials & Design. 2016 May 5;97:364-71.
13.Jiang H*, Goulbourne CN, Tatar A, Turlo K, Wu D, Beigneux AP, Grovenor CR, Fong LG, Young SG. High-resolution imaging of dietary lipids in cells and tissues by NanoSIMS analysis. Journal of lipid research. 2014 Oct 1;55(10):2156-66.
14.Jiang H*, Favaro E, Goulbourne CN, Rakowska PD, Hughes GM, Ryadnov MG, Fong LG, Young SG, Ferguson DJ, Harris AL, Grovenor CR. Stable isotope imaging of biological samples with high resolution secondary ion mass spectrometry and complementary techniques. Methods. 2014 Jul 1;68(2):317-24.
15.Goulbourne CN, Gin P, Tatar A, Nobumori C, Hoenger A, Jiang H, Grovenor CRM, Adeyo O, Esko JD, Goldberg IJ, Reue, K, Tontonoz P, Bensadoun A, Beigneux AP, Young SG, Fong LG. (2014). The GPIHBP1–LPL complex is responsible for the margination of triglyceride-rich lipoproteins in capillaries. Cell Metabolism. 2014 May 6;19(5):849-60.
16.Baboo, S., Bhushan, B., Jiang, H., Grovenor, C. R., Pierre, P., Davis, B. G., & Cook, P. R. Most human proteins made in both nucleus and cytoplasm turn over within minutes, (2014). PloS One, 9(6), e99346.
17.Rakowska PD*, Jiang H*, Ray S, Pyne A, Lamarre B, Carr M, Judge PJ, J Ravi, Gerling UIM, Koksch B, Martyna GJ, Hoogenboom BW, Watts A, Crain J, Grovenor CRM, Ryadnov MG. Nanoscale imaging reveals laterally expanding antimicrobial pores in lipid bilayers, (2013). Proc. Natl. Acad. Sci. USA, 110(22), 8918-8923, *co-first author.
18.Liu, X., S. Zhu, H. Jiang, G. Zhou, Z. Chen and D. Zhang. Sonochemical replication of chloroplast with titania for light harvesting, (2011). Ultrasonics sonochemistry 18(5): 1043-1047.
19.Zhu, S., D. Zhang, Z. Chen, G. Zhou, H. Jiang and J. Li. Sonochemical fabrication of morpho-genetic TiO2 with hierarchical structures for photocatalyst, (2010). Journal of Nanoparticle Research 12(7): 2445-2456.
20.Zhu, S., D. Zhang, Z. Chen, J. Gu, W. Li, H. Jiang and G. Zhou. A simple and effective approach towards biomimetic replication of photonic structures from butterfly wings, (2009). Nanotechnology 20(31): 315303.
Useful links
Dr. Jiang's website: www.haibojiang.com
Research profile
Research profile and publications
 

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Last updated:
Tuesday, 3 November, 2015 2:39 PM