Assoc/Prof Michael House
Research Associate Professor (Biomagnetics Group)
Academic Staff (Physics and Astrophysics)
- Contact details
- Academic Staff (Physics and Astrophysics)
The University of Western Australia (M013)
35 Stirling Highway
CRAWLEY WA 6009
- +61 8 6488 1138
- +61 8 6488 5561
- Room 3.50, Physics Building, Perth campus
- BSc PhD W.Aust.
- Born in Perth, Western Australia. BSc (Hons) in Geology and PhD in Geophysics from The University of Western Australia. After working in the mineral exploration industry between 1996 and 2002, I did a career change translating into the field of Biophysics after completing a Grad. Dip (Physics) in 2003. Since 2004 I have worked in the School of Physics where I am currently a Research Associate Professor. In 2010 I was appointed the Course Co-ordinator of the MSc (Medical Physics) course.
- Key research
- Quantitative magnetic resonance imaging (MRI) techniques to non-invasively assess human diseases including Alzheimer’s disease, liver fibrosis and steatosis, and iron overload in the brain, heart, kidneys and liver. The research program is currently divided into in-vivo studies, covering a range of patients groups, and post-mortem work.
- Understanding the magnetic resonance characteristics of magnetic nanoparticles to assist the development of new contrast agents for MRI. The aim is to develop new materials that are more efficient than current agents and that can potentially be used to target specific cells in the body.
- Approaches to loading and imaging cells with magnetic particles to enable cell tracking using MRI.
- Balasubramaniam S, Pothayee N, Lin Y, House M, Woodward RC, St. Pierre TG, Davis RM, and Riffle JS. Poly(N-isopropylacrylamide)-Coated Superparamagnetic Iron Oxide Nanoparticles: Relaxometric and Fluorescence Behavior Correlate to Temperature-Dependent Aggregation. Chemistry of Materials, 2011, 23 (14), pp 3348–3356.
Carroll MRJ, Huffstetler PP, Miles WC, Goff JD, Davis RM, Riffle JS, House MJ, Woodward RC and St Pierre TG. The effect of polymer coatings on proton transverse relaxivities of aqueous suspensions of magnetic nanoparticles. Nanotechnology, 2011, 22(32).
House MJ, St Pierre TG, Milward EA, Bruce DG, Olynyk JK. Relationship Between Brain R2 and Liver and Serum Iron Concentrations in Elderly Men. Magnetic Resonance in Medicine, 2010, 63(2), 275-281.
Carroll MRJ, Woodward RC, House MJ, Teoh WY, Amal R, Hanley TL, St Pierre TG. Experimental validation of proton transverse relaxivity models for superparamagnetic nanoparticle MRI contrast agents. Nanotechnology, 2010, 21(3).
House MJ, St. Pierre TG, and McLean C. 1.4T study of proton magnetic relaxation rates, iron concentrations and plaque burden in Alzheimer's disease and control post-mortem brain tissue. Magnetic Resonance in Medicine, 2008, 60: 41-52.
House MJ, St. Pierre TG, Kowdley K, Montine T, Connor J, Beard J, Siddaiah N, Berger J, Shankland E, Jin LW. Correlation of proton transverse relaxation rates (R2) with iron concentrations in post-mortem brain tissue from Alzheimer's disease patients. Magnetic Resonance in Medicine, 2007, 57: 172-180.
House MJ, St. Pierre TG, Foster JK, Martins RN, and Clarnette R. Quantitative MRI R2 relaxometry in elderly participants reporting memory loss. American Journal of Neuroradiology, 2006, 27: 430-439.
Haacke EM, Cheng NY, House MJ, Liu Q, Neelavalli J, Ogg RJ, Khan A, Ayaz M, Kirsch W, Obenaus A. Imaging iron stores in the brain using magnetic resonance imaging. Magnetic Resonance Imaging, 2005, 23(1): 1-25.
House M, Dentith M, Trench A, Groves D, Miller D. Structure of the highly mineralised late-Archaean granitoid-greenstone terrain and the underlying crust in the Kambalda-Widgiemooltha area, Western Australia, from the integration of geophysical datasets. Exploration Geophysics, 1999, 30: 50-67.
Trench A, House M, Miller DR, Withers JA, Goleby B, Drummond BJ. On the gravity signature of Archaean greenstones in the Widgiemooltha-Tramways area, Eastern Goldfields, Western Australia. Exploration Geophysics, 1993, 24: 811-818.
Dentith MC, House M, Ridley JR, Trench A. Three-dimensional structure of greenstone belts in Western Australia: implications for gold exploration. Exploration Geophysics, 1992, 23: 105-110.
- Future research
- Measuring liver fibrosis and fat using MRI. Finding magnetoreceptors in bees.
- International BioIron Society
American Association for the Advancement of Science
- Research profile
Research profile and publications