The University of Western Australia

UWA Staff Profile

Ipsum Lorem

Phillip Melton

Dr Phillip Melton

Head, Statistical Genetics/Senior Lecturer
Genetic Origins of Health and Disease, Centre for (GOHaD)

Contact details
Centre for Genetic Origins of Health and Disease (GOHaD)
The University of Western Australia (M409)
35 Stirling Highway
+61 8 9224 0367
Key research
Genetic epidemiology of complex disease in families.
McCarthy NS, Melton PE, Cadby G, Yazar S, Franchina M, Moses EK, Mackey DA, Hewitt AW. Meta-analysis of human methylation data for evidence of sex-specific autosomal patterns.. BMC Genomics. 15:981.

Seyerle AA, Young AM, Jeff JM, Melton PE, Jorgensen NW, Lin Y, Carty CL, Deelman E, Heckbert SR, Hindorff LA, Jackson RD, Martin LW, Okin PM, Perez MV, Psaty BM, Soliman EZ, Whitsel EA, North KE, Laston S, Kooperberg C, and CL Avery. 2014. Evidence of heterogeneity by race/ethnicity in genetic determinants of QT interval: the Population Architecture using Genomics and Epidemiology (PAGE) Study. Epidemiology 25(6)790-798.

Baldi-Salas N, Melton PE, Crawford MH. 2014. Effect of Recent Historical Events on Migration and Surname Stratification among the Rama Amerindians from Nicaragua. Human Biology. 86(1) 37-50.

Wu Z, Hu Y, Melton PE. 2014. Longitudinal data analysis for genetic studies in the whole-genome sequencing era. Genetic Epidemiology. 38 S1:S74-S80.

Melton PE, Almasy LA. 2014. Bivariate association analysis of longitudinal phenotypes in families. BMC Proceedings. 8:S90.

Bickeböller H, Bailey JN, Beyene J, Cantor RM, Cordell HJ, Culverhouse RC, Engelman CD, David Fardo DW, Ghosh S, König IR, Lorenzo-Bermejo J, Melton PE, Santorico SA, Satten GA, Sun L, Tintle NL, Ziegler A, MacCluer JW, Almasy L. 2014. Genetic Analysis Workshop 18: Methods and strategies for analysing human sequence and phenotype data in members of extended pedigrees. BMC Proceedings 8:S1.

Jones RM, Cadby G, Melton PE, Abraham L, Whitehouse AJO, Moses EK. 2013. Genome-wide association study of autistic-like traits in a general population study of young adults. Frontiers in Human Neuroscience. 11:7:658.

Cadby G, Mukherjee S, Musk AW, Reid A, Garlepp M, Dick I, Robinson C, Hui J, Fiorito G, Guarrera S, Beilby J, Melton PE, Moses E, Ugolini D, Mirabelli D, Bonassi S, Magnani C, Dianzani I, Matullo G, de Klerk N, Robinson B, Creaney J , Palmer LJ. 2013. A genome-wide association study for malignant mesothelioma risk. Lung Cancer. 82(1):1-8.

Johnson MP, Brennecke SP, East CE, Dyer TD, Roten LT, Proffitt JM, Melton PE, Fenstad MH, Aalto-Viljakainen T, Mäkikallio K, Heinonen S, Kajantie E, Kere J, and H. Laivuori for the FINNPEC Study Group, Austgulen R, Blangero J, Moses EK. 2013. Genetic dissection of the preeclampsia susceptibility locus on chromosome 2q22 reveals shared novel risk factors for cardiovascular disease. Molecular Human Reproduction. 19(7):423-37.

Melton PE, Baldi-Salas N, Barrantes R, Crawford MH. 2013. Microevolution, migration, and the population structure of five Amerindian populations from Nicaragua and Costa Rica. American Journal of Human Biology. 25(4):480-90.

Melton PE, Carless M, Curran JE, Dyer TD, Göring HH, Kent Jr. JW, Drigalenko E, Johnson MP, MacCluer JW, Moses EK, Comuzzie AG, Mahaney MC, O'Leary DH, Blangero J, Almasy LA. 2013. Genetic architecture of carotid artery intima-media thickness in Mexican Americans. Circulation: Cardiovascular Genetics. 6(2):211-221.

Rubicz R, Yolken R, Drigalenko EI, Carless M, Dyer TD , Bauman L, Melton PE, Kent J Jr, Harley JB, Curran JE, Johnson MP, Cole SA, Almasy L, Moses EK, Dhurandhar NV, Kraig E, Blangero J, Leach CT, Göring HHH. 2013. An integrative genomic study localizes factors influencing Epstein-Barr virus infection to the major histocompatibility complex region. PLoS Genet 9(1): e1003147.

Kumar S,C Bellis, M Zlojutro, PE Melton, J Blangero, JE Curran. (2011) Large Scale Mitochondrial sequencing in Mexican Americans suggests a reappraisal of Native American origins. BMC Evolutionary Biology. 11 (1), 293.

Melton PE, Pankratz N. (2011) Joint analyses of disease and correlated quantitative phenotypes using next generation sequencing data. Genetic Epidemiology 35 (S1), S67-S73.

Melton, PE, Kent Jr. JW, Dyer TD, Almasy LA, Blangero J. Genetic signal maximization using environmental regression. BMC Proceedings.5 (Suppl 9), S72.

Melton PE, K Haack, HHH Göring, S Laston, JG Umans, ET Lee, R Fabsitz, RB Devereux, LG Best, J MacCluer, LA Almasy, Cole SA (2011). Genetic influences on serum bilirubin in American Indians: The Strong Heart Family Study. American Journal of Human Biology. 23: 118-125.

Melton PE, S Rutherford, VS Voruganti, HHH Göring, S Laston, K Haack, AG Comuzzie, JE Curran,M Johnson, E Moses, TD Dyer, J Blangero, ET Lee, LG Best, RR Fabsitz, RB Devereux, PM Okin, J Bella, U Broeckel, BV Howard, JW MacCluer, SA Cole, LA Almasy. (2010) Bivariate genetic association of KIAA1797 with heart rate in American Indians: The Strong Heart Family Study. Human Mol. Genet. 19(18): 3662-3671.

Rubicz R, PE Melton, G Sun, V Spitsyn, R Deka, and MH Crawford (2010) Genetic structure of native circumpolar populations based on autosomal, mitochondrial and Y chromosome DNA markers American Journal of Physical Anthropology. 143:62-74.

Melton PE, MJ Mosher, R. Rubicz, M. Zlojutro, and MH Crawford (2010) Mitochondrial DNA diversity in Mennonites from the Midwestern United States. Human Biology. June: 82(3) 267-289.

Melton PE, I. Briceño, A. Goméz, EJ. Devor, J. Bernal and MH Crawford (2007) Biological relationship between Central and South American Chibchan speaking- populations: evidence from mtDNA. American Journal of Physical Anthropology May;133(1):753-770.

Taraskia L & P. Melton (2006) Comparative analysis of Yakut mitochondrial DNA and other Asian populations. Genetika 42(12) 1439–1446. In Russian

Melton PE, M. Zlojutro, K Kimminau, MH Crawford (2006) Biological aging and Cox hazard analysis of mortality trends in a Mennonite community from south-central Kansas. American Journal of Human Biology May-Jun;18(3):387-401.
Roles, responsibilities and expertise
Head, Statistical Genetics
Funding received
Ada Bartholomew Medical Trust
National Health & Medical Research Council
National Institute of Health
Royal Perth Hospital Medical Research Found.
Texas Biomedical Research Institute
American Assoc. of Anthropological Genetics
American Society of Human Genetics
American Association of Physical Anthropology
Human Biology Association (Fellow)
International Genetic Epidemiology Society

Previous positions
Postdoctoral Scientist, Department of Genetics, Texas Biomedical Research Institute, San Antonio, Texas, USA
Fundamentals of Genetic Epidemiology
Research profile
Research profile and publications

The University of Western Australia

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Last updated:
Tuesday, 3 November, 2015 2:39 PM