The University of Western Australia

UWA Staff Profile

Ipsum Lorem

Amelia Scaffidi

Dr Amelia Scaffidi

Research Development Adviser
Research Development (ORE)

Contact details
Address
Research Development (ORE)
The University of Western Australia (M459)
35 Stirling Highway
CRAWLEY WA 6009
Australia
Phone
+61 8 6488 7553
Email
amelia.scaffidi@uwa.edu.au
Biography
Amelia completed her PhD at the University of Western Australia, School of Medicine and Pharmacology. Her PhD which was awarded a distinction identified novel signalling pathways in human lung fibroblasts. She is a recipient of an International Marie-Curie post-doctoral fellowship. Amelia worked in the Netherlands for a Biotechnology Company, BioFocusDPI on a large scale drug discovery program which identified novel drug targets to treat cystic fibrosis. She later worked as a Scientific Advisor for BioFocusDPI and is now working as the UWA Postdoctoral Coordinator.
Publications
SCAFFIDI AK*, BERMAN J. A positive postdoctoral experience is related to quality supervision and career mentoring, collaborations, networking and a nurturing research environment. Journal of Higher Ed. 2011

SCAFFIDI AK*, Owens R. Securing a Postdoctoral Fellowship. Beyond Doctorates Down-Under. In C. Denholm and T. Evans (Eds.), ACER Press. 2009.

SCAFFIDI AK*, PECHKOVSKY DV*, HACKETT L, BALLARD J, SHAHEEN F, THOMPSON PJ, THANNICKAL VJ, KNIGHT DA. TGFB1 induces avb3 integrin expression in human lung fibroblasts via avb3 integrin, c-Src and p38MAPK DEPENDENT PATHWAY. J Biol Chem. 2008.

SCAFFIDI AK, PETROVIC N, MOODLEY YP, FOGEL-PETROVIC M, SEEBER R, EIDNE K, THOMPSON PJ. KNIGHT DA. Interaction between TGFBIIR and avb3 potentiates the proliferative effects of human lung fibroblasts. J Biol Chem. 2004; 279(36):37726-33

MOODLEY YP, CATERINA P, SCAFFIDI AK, MISSO NL, PAPADIMITRIOU JM, MCANULTY RJ, LAURENT GJ, THOMPSON PJ, KNIGHT DA.
Comparison of the morphological and biochemical changes in normal human lung fibroblasts and fibroblasts derived from lungs of patients with idiopathic pulmonary fibrosis during FasL-induced apoptosis. J Pathol 2004; 202(4):486-95.

MOODLEY YP, SCAFFIDI AK, MISSO NL, KEERTHISINGAM C, MCANULTY RJ, LAURENT GJ, MUTSAERS SE, THOMPSON PJ, AND KNIGHT DA. Fibroblasts Isolated from Normal Lungs and Those with Idiopathic Pulmonary Fibrosis Differ in Interleukin-6/gp130-Mediated Cell Signaling and Proliferation. Am J Path. 2003; 163: 345-354

MOODLEY YP, MISSO NL, SCAFFIDI AK, FOGEL-PETROVIC M, ROBIN J MCANULTY, LAURENT GJ, THOMPSON PJ AND KNIGHT DA. Inverse effects of IL-6 on apoptosis of fibroblasts from pulmonary fibrosis and normal lungs. Am J Respir Cell Mol Biol. 2003; 29:490-498

MOODLEY YP, RIGBY PJ, BLUNDELL CS, BUNT SM, HAYASHI H, MISSO NL, McANULTY RJ, KEERTHISINGAM CB, SCAFFIDI AK, THOMPSON PJ, KNIGHT DA. Macrophage recognition and phagocytosis of apoptotic fibroblasts is critically dependent of fibroblast-derived thrombospondin 1 and CD36. Am J Path. 2003; 162: 771-779

SCAFFIDI AK, MUTSAERS S, MOODLEY YP, MCANULTY RJ, LAURENT GJ, THOMPSON PJ, KNIGHT DA. Oncostatin M stimulates proliferation and inhibits apoptosis of human lung fibroblasts. B J Pharmacol. 2002; 136:793-801

KNIGHT DA, LIM S, SCAFFIDI AK, ROCHE N, FAN CHANG K, STEWART GA, THOMPSON PJ. Immunohistochemical detection of Protease Activated Receptor (PAR)-1 and PAR-2 Expression in Asthmatic airways. J Allergy Clin Immunol. 2001; 108:797-803.

SCAFFIDI AK, MOODLEY YP, WEICHSELBAUM M, THOMPSON PJ KNIGHT DA. Regulation of human lung fibroblast phenotype and behavior by vitronectin and vitronectin integrins. J Cell Sci. 2001; 114:3507-3516

WHITE JD, SCAFFIDI AK, DAVIES M, McGEACHIE J, RUDNICKI MA, GROUNDS MD. Myotube formation is delayed but not prevented in MyoD-deficient skeletal muscle: Studies in regenerating whole muscle grafts of adult mice. J Histochem Cytochem. 2000; 48:1531-1543.
Roles, responsibilities and expertise
Amelia's role as Postdoctoral Coordinator involves implementing a range of initiatives that support the professional an career development needs of Early Career Postdoctoral Researchers.
Patents
Inventors: DAVID F FISHER, AMELIA K SCAFFIDI, CARLA BERGS, HELMUTH VAN ES, RICHARD JANSSEN. Methods for identifying and compounds useful for increasing the functional activity of CF-associated mutant cystic fibrosis transmembrane conductance regulator. P31, 757 USA
Current external positions
Scientific Advisor BioFocusDPI
Research profile
Research profile and publications
 

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Last updated:
Tuesday, 3 November, 2015 2:39 PM